FREE RADICAL SCAVENGING ACTIVITY OF SIX MEDICINAL PLANTS OF BANGLADESH: A POTENTIAL SOURCE OF NATURAL ANTIOXIDANT
Department of Pharmacy, Bangladesh University, Dhaka-1207, Bangladesh.Department of Pharmaceutical Chemistry, University of Dhaka, Dhaka-1000, Bangladesh.Department of Pharmacy, University of Science and technology Chittagong, Bangladesh.Department of Pharmacy, University of Chittagong, Chittagong-4331, Bangladesh
Keywords: Ipomoea paniculata; withania somnifera; mikania cordata; abroma augusta; bombax ceiba; oxalis corniculata; antioxidant; DPPH free-radical.
The crude meoh extracts of six medicinal plants of bangladesh (ipomoea paniculata, withania somnifera, mikania cordata, abroma augusta, bombax ceiba, and oxalis corniculata) were screened for primary types of phytochemicals presence and in-vitro anti-oxidant activity by using the 1,1-diphenyl-2-picryldydrazyl-hydrate (dpph) free radical scavenging assay. Of all of them, the meoh extracts of the leaves of withania somnifera and oxalis corniculata showed strong antioxidant activity (ic50:27.8 and 19.98 ?g/ml), while the meoh extracts of ipomoea paniculata, abroma augusta and bombax ceiba showed moderate activity (ic50: 86.48, 101.4 and 58.6 ?g/ml, respectively). Moreover, mild anti-oxidant activity was observed with the meoh extract of mikania cordata (ic50 > 300 ?g/ml).