FREE RADICAL SCAVENGING ACTIVITY OF SIX MEDICINAL PLANTS OF BANGLADESH: A POTENTIAL SOURCE OF NATURAL ANTIOXIDANT
Department of Pharmacy, Bangladesh University, Dhaka-1207, Bangladesh.Department of Pharmaceutical Chemistry, University of Dhaka, Dhaka-1000, Bangladesh.Department of Pharmacy, University of Science and technology Chittagong, Bangladesh.Department of Pharmacy, University of Chittagong, Chittagong-4331, Bangladesh
Keywords: Ipomoea paniculata; withania somnifera; mikania cordata; abroma augusta; bombax ceiba; oxalis corniculata; antioxidant; DPPH free-radical.
Abstract

The crude meoh extracts of six medicinal plants of bangladesh (ipomoea paniculata, withania somnifera, mikania cordata, abroma augusta, bombax ceiba, and oxalis corniculata) were screened for primary types of phytochemicals presence and in-vitro anti-oxidant activity by using the 1,1-diphenyl-2-picryldydrazyl-hydrate (dpph) free radical scavenging assay. Of all of them, the meoh extracts of the leaves of withania somnifera and oxalis corniculata showed strong antioxidant activity (ic50:27.8 and 19.98 ?g/ml), while the meoh extracts of ipomoea paniculata, abroma augusta and bombax ceiba showed moderate activity (ic50: 86.48, 101.4 and 58.6 ?g/ml, respectively). Moreover, mild anti-oxidant activity was observed with the meoh extract of mikania cordata (ic50 > 300 ?g/ml).

Article Information

Identifiers and Pagination:
Year:2015
Volume:7
First Page:78
Last Page:84
Publisher Id:19204159.7:1.2015
Article History:
Received:December 13, 2014
Accepted:December 18, 2014
Collection year:2014
First Published:January 1, 2015


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Editor in Chief
Prof. Dr. Cornelia M. Keck (Philipps-Universität Marburg)
Marburg, Germany

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Welcome to the research group of Prof. Dr. Cornelia M. Keck in Marburg. Cornelia M. Keck is a pharmacist and obtained her PhD in 2006 from the Freie Universität (FU) in Berlin. In 2009 she was appointed as Adjunct Professor for Pharmaceutical and Nutritional Nanotechnology at the University Putra Malaysia (UPM) and in 2011 she obtained her Venia legendi (Habilitation) at the Freie Universität Berlin and was appointed as a Professor for Pharmacology and Pharmaceutics at the University of Applied Sciences Kaiserslautern. Since 2016 she is Professor of Pharmaceutics and Biopharmaceutics at the Philipps-Universität Marburg. Her field of research is the development and characterization of innovative nanocarriers for improved delivery of poorly soluble actives for healthcare and cosmetics. Prof. Keck is executive board member of the German Association of Nanotechnology (Deutscher Verband Nanotechnologie), Vize-chairman of the unit „Dermocosmetics“ at the German Society of Dermopharmacy, active member in many pharmaceutical societies and member of the BfR Committee for Cosmetics at the Federal Institute for Risk Assessment (BfR).

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Abbreviation: J App Pharm
doi: http://dx.doi.org/10.21065/19204159
Frequency: Annual 
Current Volume: 9 (2017)
Next scheduled volume: December, 2018 (Volume 10)
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Starting year: 2009
Nature: Online 
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