ANTIOXIDANT POTENTIAL AND TOTAL PHENOLIC CONTENT OF URTICA DIOICA (WHOLE PLANT)
Bhuwan Chandra Joshi, Minky Mukhija, Sushmita Semwal
Keywords: Urtica dioica Linn.(UD), DPPH assay, NO assay, Total phenolic content.
Abstract

Whole plant of Urtica dioica Linn. (Urticaceae) were subjected to extraction with different solvent according to polarity and further to obtain antioxidant rich extract. Different concentrations of different solvent extracts were subjected to antioxidant assay by DPPH, Nitric oxide NO scavenging method and Total phenolic contents. The IC50 values for different solvent extracts (Petroleum ether, ethyl acetate, n-butanol, ethanol) of Urtica dioica Linn.(UD) were found to be 215.96 ± 0.066, 78.99 ± 0.171, 168.24 ± 0.346 and 302.90 ± 0.141 respectively in comparison to L-Ascorbic acid as standard with IC50 values of 26.24 ± 0.193 respectively in DPPH model. In nitric oxide radical scavenging activity the IC50 values were found to be 172.38 ± 0.635, 101.39 ± 0.306, 141.23 ± 0.809, 202.26 ± 0.67 and 55.38 ± 0.56 for different extracts and L-Ascorbic acid respectively. The highest Total phenolic content was found to be 13.06 ± 0.15 mg GAE/g in ethyl acetate extract. However, the ethyl acetate extract showed a better free radical scavenging activity as compared to other extracts.

Article Information

Identifiers and Pagination:
Year:2015
Volume:7
First Page:98
Last Page:105
Publisher Id:19204159.7:2.2015
Article History:
Received:January 20, 2015
Accepted:March 1, 2015
Collection year:April 1, 2015
First Published:April 1, 2015


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Editor in Chief
Prof. Dr. Cornelia M. Keck (Philipps-Universität Marburg)
Marburg, Germany

Bibliography

Welcome to the research group of Prof. Dr. Cornelia M. Keck in Marburg. Cornelia M. Keck is a pharmacist and obtained her PhD in 2006 from the Freie Universität (FU) in Berlin. In 2009 she was appointed as Adjunct Professor for Pharmaceutical and Nutritional Nanotechnology at the University Putra Malaysia (UPM) and in 2011 she obtained her Venia legendi (Habilitation) at the Freie Universität Berlin and was appointed as a Professor for Pharmacology and Pharmaceutics at the University of Applied Sciences Kaiserslautern. Since 2016 she is Professor of Pharmaceutics and Biopharmaceutics at the Philipps-Universität Marburg. Her field of research is the development and characterization of innovative nanocarriers for improved delivery of poorly soluble actives for healthcare and cosmetics. Prof. Keck is executive board member of the German Association of Nanotechnology (Deutscher Verband Nanotechnologie), Vize-chairman of the unit „Dermocosmetics“ at the German Society of Dermopharmacy, active member in many pharmaceutical societies and member of the BfR Committee for Cosmetics at the Federal Institute for Risk Assessment (BfR).

Journal Highlights
Abbreviation: J App Pharm
doi: http://dx.doi.org/10.21065/19204159
Frequency: Annual 
Current Volume: 9 (2017)
Next scheduled volume: December, 2018 (Volume 10)
Back volumes: 1-9
Starting year: 2009
Nature: Online 
Submission: Online  
Language: English

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