Journal of Applied Molecular Cell Biology


ISSN: 2412-2580
Short Key Title: J App Mol Cell Bio
DOI: http://dx.doi.org/10.21065/24122580
Start Year: 2014

NO CHANCE TO FACE NSAIDs THREATENING?
Julio Padron
Studio Eutropi, Patologia Clinica e Nutrizione, Via Pompei 46, Ardea 00040, RM, Italy.
Keywords: NSAIDs, CINODs, COX-1
Abstract

Non Steroidal Anti-Inflammatory Drugs (NSAIDs), are widely used as first line of defense against most of acute and chronic inflammatory diseases. However, in spite of their apparent safer profile, as compared to steroids, they can also drive into moderate and severe reactions. Since the very beginning foremost concerns have been focused on the Gastric Damage coming from the inhibition of COX-1 derived prostaglandins, which were found to play a fundamental protective action on the overall stomach homeostasis. Thereafter indeed, most efforts to improve NSAIDs therapeutic proficiency were aimed at counteracting upper Gastrointestinal (GI) adverse reactions.

Article Information

Identifiers and Pagination:
Year:2017
Volume:4
First Page:3
Last Page:5
Publisher Id:J App Mol Cell Bio (2017 ). 4. 3-5
Article History:
Received:July 10, 2017
Accepted:July 26, 2017
Collection year:2017
First Published:July 30, 2017


© 2016 The Author(s). This open access article is distributed under a Creative Commons Attribution (CC-BY) 4.0 license. You are free to: Share — copy and redistribute the material in any medium or format Adapt — remix, transform, and build upon the material for any purpose, even commercially. The licensor cannot revoke these freedoms as long as you follow the license terms. Under the following terms: Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. No additional restrictions You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits
Editor in Chief
Bruno Perillo  (PhD)
Istituto di Scienze dell, Alimentazione, Consiglio Nazionale delle Ricerche, via Roma, 52, 83100 Avellino, Italy.

Bibliography

Dr. Bruno Perillo PhD is associated with Istituto di Scienze dell, Alimentazione, Consiglio Nazionale delle Ricerche, via Roma, 52, 83100 Avellino, Italy. He has contributed in book chapter entitled “Analysis of posttranslational modifications in the control of chromatin plasticity observed at estrogen-responsive sites in human breast cancer cells” Methods Mol. Biol. 1204, 59-69. 2014. Whereas, his research work is published in renowned credible journals.  

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Subject & Scope

  • Genomic analysis
  • Cell or tissue technologies
  • Cellular imaging
  • Gene expression analysis imaging
  • Gene transfe
  • Structural biology  
  • Molecular Cell
  • High throughput screening
  • Medical and small animal
  • Experimental organisms
  • Protein techniques
  • Signal transduction techniques
  • Etymology
  • Molecular genetics
  • Features of inheritance
  • Notation and diagrams
  • Multiple gene interactions
  • DNA and chromosomes
  • Reproduction
  • Recombination and genetic linkage
  • Gene expression
  • Genetic code
  • Nature and nurture
  • Gene regulation
  • Genetic change
  • Mutations
  • Natural selection and evolution
  • Model organisms
  • Medicine
  • Research methods
  • DNA sequencing and genomics
  • Classical, Clinical and Developmental immunology
  • Immunotherapy
  • Diagnostic immunology
  • Cancer immunology
  • Carbohydrates
  • Lipids
  • Proteins
  • Nucleic acids
  • Metabolism
  • Carbohydrates as energy source
  • Glycolysis (anaerobic and aerobic)
  • Gluconeogenesis
  • Molecular cloning
  • Polymerase chain reaction (PCR)
  • Gel electrophoresis
  • Macromolecule blotting and probing
  • Microarrays
  • Allele-specific oligonucleotide

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