of current study showedsignificant in
vivo antioxidant potential of Phyllanthus
emblicus as it increased oxidative stress biomarkers in tissue homogenates.
Biochemical tests on serum also revealed hepato-renal curative effect and
hypolipidemic effect. From the results, it had been observed that Phyllanthus emblicus antioxidant
activity was greater than the combined effect of vitamin E and C.It may be
concluded from the findings that Phyllanthus
emblicus extract at the dose of 500mg/kg could be an effective and novel
approach for treating oxidative stress induced pathological conditions.
antioxidant enzyme levels in mice. It manifested hypolipidemic, hepato-renal
curative effects. Its adjuvant use with standard therapies may help to resolve
1. Pozharitskaya ON, Ivanova SA, Shikov AN, Makarov
VG. Separation and evaluation of free radical-scavenging activity of phenol
components of Emblica officinalis extract by using an HPTLC-DPPH method. J.
Sep. Sci.2007; 30:1250-1254.
2. Ngamkitidechakul C, Jaijoy K, Hansakul P, Soonthornchareonnon N,
Sireeratawong, S. Antitumour effects of Phyllanthus
emblica L. Induction of cancer cell apoptosis and Inhibition of in vivo
tumour promotion and in vitro invasion of human cancer cells. Phytother. Res.
2010; 24 (9): 1405 1413.
3. Rudnick MR, Goldfarb S, Tumlin J. Contrast-induced
nephropathy: is the picture any clearer? Clin. J. Am. Soc. Nephrol. 2008;
4. Firoj A, Amirul IM, Mustafizur R M. Antibacterial activity
of Leonurus sibiricus aerial parts.
5. Chatterjee A, Chattopadhyay S, Bandyopadhyay SK.Biphasic
Effect of Phyllanthus emblica L.
Extract on NSAID-Induced Ulcer: An Anti-oxidative TrailWeaved with
Immunomodulatory Effect.Evid. Based Complement. Alternat. Med.2011;
6. Mathur R, Sharma A, Dixit VP,
Varma M. Hypolipidemic effect of fruit juice of Emblica officinalis in
cholesterol – fed rabbits. J. Ethnopharmacol. 1996;50:61–68.
7. Naik GH, Priyadarsini KI, Bhagirathi RG, Mishra
B, Mishra KP, Banavalikar MM, Mohan H. In vitro antioxidant studies and free
radical reactions of triphala, an ayurvedic formulation and its constituents.
Phytother Res. 2005; 19:582–586.
8. Kusirisin W, Srichairatanakool S, Lerttrakarnnon P, Lailerd
N, Suttajit M, Jaikang C, Chaiyasut C. Antioxidative activity, polyphenolic
content and anti-glycation effect of some Thai medicinal plants traditionally
used in diabetic patients. Med. Chem. 2009; 5(2):139–147.
9. Nosalova G,Mokry J,Hassan KM.Antitussive activity of the fruit
extract of Emblica officinalis
Gaertn. (Euphorbiaceae) Phytomedicine. 2003; 10(6-7):583-589.
10. Saha A, Masud MA, Bachar SC, Kundu JK, Datta BK, Nahar L,
Sarker SD. The analgesic and anti-Inflammatory activities of the extracts of Phyllanthus reticulatus in mice model.
Pharm. Biol. 2007; 45(5):355-359.
11. Ahmed F, Selim MS, Das AK, Choudhuri MS. Anti-inflammatory
and antinociceptive activities of Lippia
nodiflora Linn. Pharmazie. 2004; 59(4):329-330.
12. Vasudevan M, Parle M.Memory enhancing activity of Anwala
churna (Emblica officinalis Gaertn.): An ayurvedic preparation. Physiol. Behav.
2007; 91: 46-54.
13. Moros W B, Nascimento M C, Pereira B M, Pereira NA. Plant
natural products active against snake bite-the molecular approach.
Phytochemisry. 2000; 55: 627-642
14. Moron M J, Depierre JW, Mannlrvik B. Levels of
GSH, GR and GST activities in rat lungs and liver. Biochem. Biophys. Acta.
1979; 582 (1): 67-78.
15. Aebi H. Catalase. Methods in enzymatic analysis. New York:
Academic press. 1974; 276-289.
16. Kakkar P, Das B, Viswanathan PN. A modified
spectrophotometric assay of superoxide dismutase. Ind. J. Biochem. Biophys.
17. Ohkawa H, Ohishi N, Yagi K:Assay for lipid peroxides in
animal tissues by thiobarbituric acid reaction. Anal. Biochem. 1979; 95: