Canadian Journal of Applied Sciences


ISSN: 1925-7430
Short Key Title: Can J App Sci
DOI: http://dx.doi.org/10.21065/19257430
Start Year: 2011

EVALUATION OF HYPOTENSION AND ALLERGIC REACTION WITH PARENTERAL DROTAVERINE IN A TERTIARY CARE HOSPITAL
Sidrah Andleeb, Eman Tahir, Omar Akhlaq Bhutta, Shahbaz Ahmad Khan, Saba Mazhar
Department of pharmaceutical services, Shaukat Khanum Memorial Cancer Hospital & Research Center (SKMCH&RC). 7 A Block R3 Johar Town Lahore, Pakistan.
Keywords: : Drotaverine, visceral pain, hypotension
Abstract

Background: Drotaverine is an excellent anti-spasmodic and a vital drug for relieving spastic visceral pain. However, the incidence of hypotension and allergic skin reactions is a concern with drotaverin’es use. Aim: This study was intended to evaluate the risk of adverse effects with drotaverine in hospital patients. Method: It was a retrospective cross-sectional study for the total cases on drotaverine inj. for the year 2017. Data collection form was used. Results: 1 out of a total of 62 patients suffered hypotension after administration of drotaverine injection (0.016%). Patient suffering hypotension was on dimenhydrinate injection q8hrs. regularly. There was no case of allergic skin reaction with the use. Conclusion: Use of drotaverine is safe with due consideration to mild risk of hypotension. Regular use of hypotensive drugs should be watched for while using drotaverine.

Article Information

Identifiers and Pagination:
Year:2017
Volume:7
First Page:01
Last Page:04
Publisher Id:Can J App Sci (2017 ). 7. 01-04
Article History:
Received:November 17, 2017
Accepted:December 13, 2017
Collection year:2017
First Published:December 19, 2017


© 2016 The Author(s). This open access article is distributed under a Creative Commons Attribution (CC-BY) 4.0 license. You are free to: Share — copy and redistribute the material in any medium or format Adapt — remix, transform, and build upon the material for any purpose, even commercially. The licensor cannot revoke these freedoms as long as you follow the license terms. Under the following terms: Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. No additional restrictions You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits
Editor in Chief
Xianghui Qi (PhD)
Jiangsu University, Zhenjiang, China

Bibliography

Dr. Xianghui Qi is working as Professor in the School of Food & Biological Engineering, Jiangsu University, China. His research interests: Biosynthesis of high value-added chemicals by microbes and engineered strains; Discovery of novel genes, enzymes and new strains; Rational & Irrational design of microbial enzymes; Isolation, identification and evolution of microbes; Metabolic engineering & Pathway engineering of functional microbes, and biotransformation; Metabolic regulation based on the research of microbial omics; Application of high value-added products including functional sugar alcohols by biosynthesis and biotransformation based on microbial engineered strains.

Journal Highlights
Abbreviation: Can J Appl Sci
doi: http://dx.doi.org/10.21065/19257430
Frequency: Annual
Current Volume: 7 (2017)
Next scheduled volume: December, 2018  
Back volumes: 1-7
Starting year: 2011
Nature: Online
Submission: Online
Language: English

Subject & Scope
  • Biochemistry and Biotechnology
  • Bioinformatics and Biometric
  • Chemical Technology
  • Dentistry and Hygiene
  • Environmental Health, Safety and Allied Sciences
  • Food and Nutrition
  • Health Management
  • Medical Sciences
  • Molecular/ Cellular Biology
  • Pharmaceutical Sciences
  • Pharmacotherapy
  • Theoretical Models (health, life and clinical practice)
  • Veterinary, Fishery and Animal Biology

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