Editor in Chief
Prof. Dr. Cornelia M. Keck
Philipps-Universität Marburg
Marburg, Germany

Bibliography
Welcome to the research group of Prof. Dr. Cornelia M. Keck in Marburg. Cornelia M. Keck is a pharmacist and obtained her PhD in 2006 from the Freie Universität (FU) in Berlin. In 2009 she was appointed as Adjunct Professor for Pharmaceutical and Nutritional Nanotechnology at the University Putra Malaysia (UPM) and in 2011 she obtained her Venia legendi (Habilitation) at the Freie Universität Berlin and was appointed as a Professor for Pharmacology and Pharmaceutics at the University of Applied Sciences Kaiserslautern. Since 2016 she is Professor of Pharmaceutics and Biopharmaceutics at the Philipps-Universität Marburg. Her field of research is the development and characterization of innovative nanocarriers for improved delivery of poorly soluble actives for healthcare and cosmetics. Prof. Keck is executive board member of the German Association of Nanotechnology (Deutscher Verband Nanotechnologie), Vize-chairman of the unit „Dermocosmetics“ at the German Society of Dermopharmacy, active member in many pharmaceutical societies and member of the BfR Committee for Cosmetics at the Federal Institute for Risk Assessment (BfR).
Journal Highlights
Abbreviation: J App Pharm
doi: http://dx.doi.org/10.21065/19204159
Frequency: Annual 
Current Volume: 9 (2017)
Next scheduled volume: December, 2018 (Volume 10)
Back volumes: 1-9
Starting year: 2009
Nature: Online 
Submission: Online  
Language: English

CALIBRATING HYDROGELS FOR DELIVERY OF BIOLOGICS
Kamla Pathak.
Pharmacy College Saifai, Uttar Pradesh University of Medical Sciences, Etawah 206130, Uttar Pradesh, India.
Keywords: Hydrogels, biologics, sustained release.
Abstract

In the past decade, depot systems for tissue engineering, cell therapy, biomedical research, and therapeutic proteins, have been extensively investigated. Hydrogels offer an interesting platform for sustained delivery of biologicals as these can be readily formulated with limited impact on their integrity and stability. Their high-water content and porous structures make them especially suitable for loading with therapeutic proteins However, relatively rapid release of the hydrophilic compounds (period of hours to days) and limited drug loading capacity (<10%) present major challenges. Cleavable cross-linker or hydrogels that respond to an external trigger such as ultrasound have been suggested as suitable alternatives. However, scale-up and cost-effective manufacturing using safe and established excipients remains a challenge and hydrogels for biologicals are at present scarcely developed beyond the clinical evaluation phases. While some commercial products are available the future of hydrogels for biologicals depends on the medical needs, the general benefit/risk balance, and overall costs.

Article Information

Identifiers and Pagination:
Year:2018
Volume:10
First Page:01
Last Page:05
Publisher Id:JAppPharm (2018 ). 10. 01-05
Article History:
Received:May 3, 2018
Accepted:May 17, 2018
Collection year:2018
First Published:May 22, 2018


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Subject & Scope
  • Pharmaceutics
  • Physical Pharmacy 
  • Dosage Forms Science 
  • Pharmaceutical Microbiology & Immunology 
  • Industrial Pharmacy 
  • Bio-Pharmaceutics 
  • Pharmaceutical Chemistry 
  • Pharmaceutical Instrumentation 
  • Medicinal Chemistry 
  • Pharmacognosy 
  • Physiology &Histology 
  • Anatomy & Pathology 
  • Pharmacology & Therapeutics 
  • Pharmacy Practice 
  • Pharmaceutical Mathematics   
  • Biostatistics 
  • Dispensing 
  • Community Social & Administrative Pharmacy 
  • Hospital Pharmacy 
  • Clinical Pharmacy 
  • Pharmaceutical Quality Management 
  • Forensic Pharmacy 
  • Pharmaceutical Technology 
  • Pharmaceutical Management & Marketing

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