EFFICACY OF MALAYSIAN HERBAL PRODUCT IN TREATING DIABETES MELLITUS
Sadia Saleem Rao1, Rahila Najam1, Syed Atif Abbas2
1. Department of Pharmacology, Faculty of Pharmacy, University of Karachi, Karachi-75270, Pakistan
2. Jalan Taylor's 47500 Subang Jaya, Selangor Darul Ehsan Malaysia.
Keywords: Alloxan, Momordica charantia, Punica granatum, Lawsonia inermis and Tamarindus indica.
Aim of the study was to examine the efficacy of a combination herbal product from Malaysian market. This herbal product is traditionally being used for managing diabetes mellitus. The herbal combination is a mixture of Momordica charantia, Punica granatum, Lawsonia inermis and Tamarindus indica. The drug was administered orally at the dose of 620mg/70kg once daily for the duration of 42 days to alloxan induced diabetic rats. The effects of this herbal combination were compared with standard drug, sulphonylurea (Glibenclamide). Efficacy of the drug was monitored at intervals with respect to fasting and random glucose levels and glycosylated hemoglobin. Results revealed that the combination of four herbs reduced fasting glucose levels and random glucose levels. HbA1C was observed to be less than 7% by this herbal combination. However, the herbal combination failed to produce the efficacy comparable to the standard drug, Glibenclamide.
© 2016 The Author(s). This open access article is distributed under a Creative Commons Attribution (CC-BY) 4.0 license.
You are free to:
Share — copy and redistribute the material in any medium or format
Adapt — remix, transform, and build upon the material for any purpose, even commercially.
The licensor cannot revoke these freedoms as long as you follow the license terms.
Under the following terms:
Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made.
You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
No additional restrictions
You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits