Canadian Journal of Applied Sciences

ISSN: 1925-7430
Short Key Title: Can J App Sci
Start Year: 2011

Faiza Rasheed, Waqas Khan Kayani, Adeel Mahmood and Muhammad Gulfraz
1. *Department of Agro systems, P.O Box 104, The Swedish University of Agriculture Sciences, SE 230 53, Alnarp, Sweden 2. Molecular Biology Laboratory, Department of Biochemistry, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, 45320, Pakistan 3. Department of Plant Sciences, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, 45320, Pakistan 4. Department of Biochemistry, PMAS Arid Agriculture University Rawalpindi, Pakistan.
Keywords: Justicia adhatoda, Phtochemicals, Antimicrobial compounds, Bioactivity

In vitro antibacterial and antioxidant activities of various leaf extracts of Justicia adhatoda L. (locally known as Bhaikar) were assessed. The leaves were also subjected to various phytochemical analysis. Results revealed that leaves of J. adhatoda L. contain significant amount of total alkaloid, phenols flavonoid, saponins, tannins , protein, crude oil, dietary fiber, essential and non essential metal ions. The methanol, ethanol, butanol, chloroform and n-hexane leaf extracts of J. adhatoda significantly inhibited the growth of all bacteria tested as compared to standard antibiotic. However, acetone and aqueous leaf extracts of J. adhaotda were not effective against any bacteria. Methanol extract of J. addhatoda provide lowest Minimum Inhibitory Concentration (MIC) for E. coli (1.0 mg/ml ) followed by Klebsella. pneumoni ( 1.2 mg/ml), where as MIC values of other solvent extracts were in the order of ethanol > chloroform>n-hexane > butanol. The order of antioxidant activities of various leaf extracts found in different solvent extractions was ethanol >methanol >chloroform> water> butanol>. This study will help to promote scientifically use of J. adhatoda in local medicine as well as its use as an important raw material for pharmaceutical industries.

Article Information

Identifiers and Pagination:
First Page:1
Last Page:17
Publisher Id:CanJAppSci (2013 ). 3. 1-17
Article History:
Received:September 19, 2012
Accepted:December 11, 2012
Collection year:2013
First Published:January 1, 2013

© 2016 The Author(s). This open access article is distributed under a Creative Commons Attribution (CC-BY) 4.0 license. You are free to: Share — copy and redistribute the material in any medium or format Adapt — remix, transform, and build upon the material for any purpose, even commercially. The licensor cannot revoke these freedoms as long as you follow the license terms. Under the following terms: Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. No additional restrictions You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits
Editor in Chief
Xianghui Qi (PhD)
Jiangsu University, Zhenjiang, China


Dr. Xianghui Qi is working as Professor in the School of Food & Biological Engineering, Jiangsu University, China. His research interests: Biosynthesis of high value-added chemicals by microbes and engineered strains; Discovery of novel genes, enzymes and new strains; Rational & Irrational design of microbial enzymes; Isolation, identification and evolution of microbes; Metabolic engineering & Pathway engineering of functional microbes, and biotransformation; Metabolic regulation based on the research of microbial omics; Application of high value-added products including functional sugar alcohols by biosynthesis and biotransformation based on microbial engineered strains.

Journal Highlights
Abbreviation: Can J Appl Sci
Frequency: Annual
Current Volume: 7 (2017)
Next scheduled volume: December, 2018  
Back volumes: 1-7
Starting year: 2011
Nature: Online
Submission: Online
Language: English

Subject & Scope
  • Biochemistry and Biotechnology
  • Bioinformatics and Biometric
  • Chemical Technology
  • Dentistry and Hygiene
  • Environmental Health, Safety and Allied Sciences
  • Food and Nutrition
  • Health Management
  • Medical Sciences
  • Molecular/ Cellular Biology
  • Pharmaceutical Sciences
  • Pharmacotherapy
  • Theoretical Models (health, life and clinical practice)
  • Veterinary, Fishery and Animal Biology

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