Canadian Journal of Applied Sciences

ISSN: 1925-7430
Short Key Title: Can J App Sci
Start Year: 2011

K. H. Kumar Naik, B. Ashok, Avinash Prakashab, Nagaraja Naika
1. Department of Studies in Chemistry,University of Mysore, Manasagangotri,Mysore-06, India. 2. Department of studies in biotechnology,University of Mysore, Manasagangotri, Mysore-06, Karnataka, India.
Keywords: Schiff bases, Metal complexes, Enzymatic activity, DPPH Assay, Antimicrobial activity.

In the present study, we synthesized Novel ligand and their metal complexes with 8-((2-(2,4-dinitrophenyl)hydrazono)methyl)-7-hydroxy-4-methyl-2H-chromen-2-one ligand. The colored complexes were prepared by the addition of chloride salts of Manganese(II), Cobalt(II), Nickel(II) and Copper(II) to a solution of ligand. In conclusion, the structures of the obtained complexes were characterized by FT-IR, elemental analysis, UV-spectral studies, conductmetric and magnetic susceptibility measurements. The synthesized metal complexes were investigated for biological activities. Enzymatic inhibition activity has been done by using acetylcholinesterase (AChE) enzyme, antioxidant activity by DPPH assay and also the antimicrobial studies. All tested metal complexes and ligand reveal effective biological activities.

Article Information

Identifiers and Pagination:
First Page:90
Last Page:107
Publisher Id:CanJAppSci (2013 ). 3. 90-107
Article History:
Received:June 11, 2013
Accepted:July 29, 2013
Collection year:2013
First Published:October 1, 2013

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Editor in Chief
Xianghui Qi (PhD)
Jiangsu University, Zhenjiang, China


Dr. Xianghui Qi is working as Professor in the School of Food & Biological Engineering, Jiangsu University, China. His research interests: Biosynthesis of high value-added chemicals by microbes and engineered strains; Discovery of novel genes, enzymes and new strains; Rational & Irrational design of microbial enzymes; Isolation, identification and evolution of microbes; Metabolic engineering & Pathway engineering of functional microbes, and biotransformation; Metabolic regulation based on the research of microbial omics; Application of high value-added products including functional sugar alcohols by biosynthesis and biotransformation based on microbial engineered strains.

Journal Highlights
Abbreviation: Can J Appl Sci
Frequency: Annual
Current Volume: 7 (2017)
Next scheduled volume: December, 2018  
Back volumes: 1-7
Starting year: 2011
Nature: Online
Submission: Online
Language: English

Subject & Scope
  • Biochemistry and Biotechnology
  • Bioinformatics and Biometric
  • Chemical Technology
  • Dentistry and Hygiene
  • Environmental Health, Safety and Allied Sciences
  • Food and Nutrition
  • Health Management
  • Medical Sciences
  • Molecular/ Cellular Biology
  • Pharmaceutical Sciences
  • Pharmacotherapy
  • Theoretical Models (health, life and clinical practice)
  • Veterinary, Fishery and Animal Biology

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