Canadian Journal of Applied Sciences

ISSN: 1925-7430
Short Key Title: Can J App Sci
Start Year: 2011

Ashfaq Ahmad, Khurram Afzal, Naeem Riaz, Huda Jamal, Saba Faryad, Farzana Zafar
1School of Pharmacy, The University of Lahore, (Islamabad Campus), Islamabad, Pakistan. 2Riphah Institute of Pharmaceutical Sciences, Islamabad, Pakistan.
Keywords: Myocardial infarction, atherosclerosis, Diuretic

Myocardial infarction is simply due to decreased supply of oxygen and blood to the particular tissue of heart which ultimately leads to the death of tissue. Naturally heart is quite stable in its involuntary action due to balance between oxygen supply and oxygen demand of the cardiac muscle. when this balance is disturbed by the clot formation(atherosclerosis) in coronary artery or increased demand of oxygen due to increased heart rate then clinical situation arises as tightening of chest,laboured breathing, sweating and radiating pain originating form chest and terminating to left arm and jaws as well. A male of 55 years was hospitalized in one of the most well reputed hospital of Federal area of Pakistan. The patients was nimble due to cold sweating, sever radiating left sided chest pain and was in the state of fear and apprehension. As an acute case of M.I, patient was initially treated with thrombolytic agent, Streptokinase injection 1.5 MIU through I.V infusion in one hour, tab lowplat (Clopidogrel), tab Loprin (asprin), tab Lasix (Diuretic) and tab digoxin 0.25 mg for limited days. Urine and blood samples were collected to investigate the cause and mitigate the worst clinical situation. Laboratory finding showed normal results and controlled lipid profile. Most important cardiac enzymes were in normal function .After the six days of careful monitoring, patient was discharged by prescribing tab loprin75 mg,tab lowplat 75 mg tab Lasix 40 mg,tab digoxin 0.25 mg and with precautionary measurements regarding diet control to prevent another incidence.Inview to provide aggressive therapy to save life in emergency situation, rational use of medicinal agents was neglected and prescription errors have been identified which can further worse the situation.

Article Information

Identifiers and Pagination:
First Page:10
Last Page:15
Publisher Id:CanJAppSci (2011 ). 1. 10-15
Article History:
Received:January 13, 2011
Accepted:February 21, 2011
Collection year:2011
First Published:March 5, 2011

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Editor in Chief
Xianghui Qi (PhD)
Jiangsu University, Zhenjiang, China


Dr. Xianghui Qi is working as Professor in the School of Food & Biological Engineering, Jiangsu University, China. His research interests: Biosynthesis of high value-added chemicals by microbes and engineered strains; Discovery of novel genes, enzymes and new strains; Rational & Irrational design of microbial enzymes; Isolation, identification and evolution of microbes; Metabolic engineering & Pathway engineering of functional microbes, and biotransformation; Metabolic regulation based on the research of microbial omics; Application of high value-added products including functional sugar alcohols by biosynthesis and biotransformation based on microbial engineered strains.

Journal Highlights
Abbreviation: Can J Appl Sci
Frequency: Annual
Current Volume: 7 (2017)
Next scheduled volume: December, 2018  
Back volumes: 1-7
Starting year: 2011
Nature: Online
Submission: Online
Language: English

Subject & Scope
  • Biochemistry and Biotechnology
  • Bioinformatics and Biometric
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  • Food and Nutrition
  • Health Management
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  • Molecular/ Cellular Biology
  • Pharmaceutical Sciences
  • Pharmacotherapy
  • Theoretical Models (health, life and clinical practice)
  • Veterinary, Fishery and Animal Biology

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