Kundan Singh Bora, Aruna Dubey
Sardar Bhagwan Singh Post Graduate Institute of Biomedical Sciences & Research, Balawala, Dehradun, Uttarakhand – 248 161, India
Keywords: Melissa parviflora, pharmacognostic standards, physico-chemical parameters, quality control

Objectives: Melissa parviflora (family: Lamiaceae) has been traditionally used as a tranquillizer, relaxants, nervine and sleeping aids throughout the world. The plant is widely valued for its calming properties and has a tonic effect on the heart but no work has ever been carried out for standardizing this potential plant. The present study was designed to establish macroscopic and microscopic determinations, and physico-chemical parameters for Melissa parviflora stem. Methods: WHO recommended methods and other standard procedures were employed for the establishment of pharmacognostic and physico-chemical parameters. Results: TS of M. parviflora stem under the microscope showed an epidermal layer, cortex, continuous thin cylinder of vascular tissues, uniseriate medullary rays and wide pith. The xylem segments posses several wide annular vessels. Glandular sessile trichomes and multicellular covering trichomes were also appeared in the TS of stem. The powdered drug under the microscope showed fragments of parenchymatous tissue with intercellular spaces and strands of vascular bundles. Epidermis appeared double layered elongated cell wall in surface view with papilla present in between the cells. Abundant simple multicellular covering trichomes and occasionally sessile glandular trichomes were found. Abundant annular types of xylem vessels and prismatic calcium oxalate crystals were present in the powdered drug. Physico-chemical parameters help to identify authentic plant material and check adulteration. In the present study different ash values and extractive values were also determined. Conclusion: The findings of the present study could be useful in setting some diagnostic indices for the identification and preparation of a monograph of M. parviflora.

Article Information

Identifiers and Pagination:
First Page:173
Last Page:181
Publisher Id:19204159.7:4.2015
Article History:
Received:July 13, 2015
Accepted:July 22, 2015
Collection year:2015
First Published:October 1, 2015

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Editor in Chief
Prof. Dr. Cornelia M. Keck (Philipps-Universität Marburg)
Marburg, Germany


Welcome to the research group of Prof. Dr. Cornelia M. Keck in Marburg. Cornelia M. Keck is a pharmacist and obtained her PhD in 2006 from the Freie Universität (FU) in Berlin. In 2009 she was appointed as Adjunct Professor for Pharmaceutical and Nutritional Nanotechnology at the University Putra Malaysia (UPM) and in 2011 she obtained her Venia legendi (Habilitation) at the Freie Universität Berlin and was appointed as a Professor for Pharmacology and Pharmaceutics at the University of Applied Sciences Kaiserslautern. Since 2016 she is Professor of Pharmaceutics and Biopharmaceutics at the Philipps-Universität Marburg. Her field of research is the development and characterization of innovative nanocarriers for improved delivery of poorly soluble actives for healthcare and cosmetics. Prof. Keck is executive board member of the German Association of Nanotechnology (Deutscher Verband Nanotechnologie), Vize-chairman of the unit „Dermocosmetics“ at the German Society of Dermopharmacy, active member in many pharmaceutical societies and member of the BfR Committee for Cosmetics at the Federal Institute for Risk Assessment (BfR).

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Abbreviation: J App Pharm
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Current Volume: 9 (2017)
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Starting year: 2009
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