Tasneem Farasat*, Tahira Mughal*, Ayesha Liaqat *
*Zoology Department, Lahore College for Women University, Lahore, Pakistan **Botany department Lahore College for Women University, Lahore, Pakistan
Keywords: Thyroid dysfunction, hypothyroid, hyperthyroid

Thyroid dysfunction is the common endocrine disorder and females are more affected than males. The aim of this study was to assess the serum thyroid hormones level in premenopausal and postmenopausal females with thyroid dysfunction and observed the effect of thyroid dysfunction on body weight and menstrual regularity. Total 91 female subjects were included in the study. Serum thyroid hormone levels of TSH, FT3 and FT4 were assessed by ELISA technique. It was concluded from the present study that serum TSH levels were significantly higher in premenopausal and postmenopausal hypothyroid females as compared to the control group (P<0.01). In hyperthyroid premenopausal females serum TSH level was significantly lower from the control group (P<0.01). Serum FT3 level was significantly higher in hyperthyroid premenopausal and postmenopausal females as compared to control group (P<0.01). In this study, 80% of premenopausal hypothyroid females and 65% of hyperthyroid females complained about menstrual irregularities, this percentage is high as compared to control subjects which is 20% (P<0.01). Inverse negative correlation was observed between TSH, T3, TSH, and T 4, whereas positive correlation was observed between T3 and T 4. Thyroid dysfunction can lead to menstrual irregularities and infertility.

Article Information

Identifiers and Pagination:
First Page:33
Last Page:44
Publisher Id:JAppPharm (2011 ). 3. 33-44
Article History:
Received:September 15, 2010
Accepted:December 21, 2010
Collection year:2010
First Published:January 11, 2011

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Editor in Chief
Prof. Dr. Cornelia M. Keck (Philipps-Universität Marburg)
Marburg, Germany


Welcome to the research group of Prof. Dr. Cornelia M. Keck in Marburg. Cornelia M. Keck is a pharmacist and obtained her PhD in 2006 from the Freie Universität (FU) in Berlin. In 2009 she was appointed as Adjunct Professor for Pharmaceutical and Nutritional Nanotechnology at the University Putra Malaysia (UPM) and in 2011 she obtained her Venia legendi (Habilitation) at the Freie Universität Berlin and was appointed as a Professor for Pharmacology and Pharmaceutics at the University of Applied Sciences Kaiserslautern. Since 2016 she is Professor of Pharmaceutics and Biopharmaceutics at the Philipps-Universität Marburg. Her field of research is the development and characterization of innovative nanocarriers for improved delivery of poorly soluble actives for healthcare and cosmetics. Prof. Keck is executive board member of the German Association of Nanotechnology (Deutscher Verband Nanotechnologie), Vize-chairman of the unit „Dermocosmetics“ at the German Society of Dermopharmacy, active member in many pharmaceutical societies and member of the BfR Committee for Cosmetics at the Federal Institute for Risk Assessment (BfR).

Journal Highlights
Abbreviation: J App Pharm
Frequency: Annual 
Current Volume: 9 (2017)
Next scheduled volume: December, 2018 (Volume 10)
Back volumes: 1-9
Starting year: 2009
Nature: Online 
Submission: Online  
Language: English

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