THE USE OF PLANT EXTRACT IN A MOUSE MODEL OF DEPRESSION: A REVIEW
Alamgeer, Taseer Ahmad, Iradat Hussain, Muhammad Naveed Mushtaq...
1. Faculty of Pharmacy University of Sargodha, Sargodha, Pakistan
2. Shifa Institute of Pharmaceutical Sciences, Shifa Tameer-e-Millat University, Islamabad
3. Riphah Institute of pharmaceutical sciences, Riphah International University, Islamabad
4. Margalla College of pharmacy, Margalla Institute of Health and Sciences, Rawalpendi
Keywords: Plant extract, depression, animal model, herbal medicine.
Depression is a mood disorder which is among the most dominant forms of psychiatric disorders and a major cause for morbidity and mortality. Since, many synthetic drugs are being used as anti-depressant, but due to adverse effects it leads to patient non-compliance. Thus, there is a need to search for plants oriented anti-depressant drugs and also develop a suitable animal model to clearly elucidate its effects. A number of medicinal plants have shown anti-depressant activities. This review attention is towards plant extract and its use in best animal model which will certainly highlights their influence on the development of novel therapeutic drugs.
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