PROCESS STRATEGIES FOR ALKALINE LIPASE PRODUCTION USING Aspergillus Niger MTCC 2594
Suraj Abraham ,2,3*; Numbi Ramudu Kamini3 and Marichetti Kuppuswami Gowthaman3
1. Biological Sciences Group, Faculty division III, Birla Institute of Technology & Science, Vidhya Vihar Campus, Pilani, 333 031, India 2. Department of Anatomy & Cell biology, College of Medicine, University of Saskatchewan, Saskatoon, SK, S7N 5E5, Canada 3. Department of Biotechnology, Central Leather Research Institute, Adyar, Chennai, 600 020, India
Keywords: Aspergillus niger MTCC 2594, substrate inhibition, Fed batch, Production, Shake flask, Submerged stir tank fermenter]
Abstract

We report scale-up production of alkaline lipases from Aspergillus niger MTCC 2594 using submerged stir tank fermenter (SSTF). The batch culture experiments and biomass studies suggest that olive oil used in the process reduced enzyme yield. We found that the addition of olive oil intermittently might be a potential fed-batch strategy to improve lipase production using Aspergillus niger MTCC 2594.

Article Information

Identifiers and Pagination:
Year:2011
Volume:3
First Page:1
Last Page:8
Publisher Id:JAppPharm (2011 ). 3. 1-8
Article History:
Received:October 2010
Accepted:December 17, 2010
Collection year:201
First Published:January 11, 2011


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Editor in Chief
Prof. Dr. Cornelia M. Keck (Philipps-Universität Marburg)
Marburg, Germany

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Welcome to the research group of Prof. Dr. Cornelia M. Keck in Marburg. Cornelia M. Keck is a pharmacist and obtained her PhD in 2006 from the Freie Universität (FU) in Berlin. In 2009 she was appointed as Adjunct Professor for Pharmaceutical and Nutritional Nanotechnology at the University Putra Malaysia (UPM) and in 2011 she obtained her Venia legendi (Habilitation) at the Freie Universität Berlin and was appointed as a Professor for Pharmacology and Pharmaceutics at the University of Applied Sciences Kaiserslautern. Since 2016 she is Professor of Pharmaceutics and Biopharmaceutics at the Philipps-Universität Marburg. Her field of research is the development and characterization of innovative nanocarriers for improved delivery of poorly soluble actives for healthcare and cosmetics. Prof. Keck is executive board member of the German Association of Nanotechnology (Deutscher Verband Nanotechnologie), Vize-chairman of the unit „Dermocosmetics“ at the German Society of Dermopharmacy, active member in many pharmaceutical societies and member of the BfR Committee for Cosmetics at the Federal Institute for Risk Assessment (BfR).

Journal Highlights
Abbreviation: J App Pharm
doi: http://dx.doi.org/10.21065/19204159
Frequency: Annual 
Current Volume: 9 (2017)
Next scheduled volume: December, 2018 (Volume 10)
Back volumes: 1-9
Starting year: 2009
Nature: Online 
Submission: Online  
Language: English

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